Wednesday, March 20 at 12:00pm to 1:00pm
Zilkha Neurogenetic Institute (ZNI), Herklotz Seminar Room
1501 San Pablo, Los Angeles, CA 90033
With a growing patient population and disappointing results from clinical trials, neurodegenerative diseases present a pressing public health crisis. We need new approaches to understand the fundamental biology of these diseases to develop therapeutic and preventative strategies. Population studies have identified genetic risk factors for late-onset forms of neurodegenerative diseases like Alzheimer’s disease (AD).
My research has focused on (1) understanding the molecular mechanisms by which neurodegenerative disease risk factors impact cellular physiology and (2) modulating these pathways as potential therapeutic strategies. To do this, I have used a suite of tools from single-molecule fluorescence to induced pluripotent stem cell (iPSC)-derived brain tissue.