USC Stem Cell Special Seminar: Andy Groves, Baylor College of Medicine—"The Potential and Pitfalls of Hair Cell Regeneration by Transcription Factor Reprogramming"

Wednesday, October 26, 2022 at 3:00pm to 4:00pm

This is a past event.

Broad CIRM Center (BCC), BCC 101
1425 San Pablo Street, Los Angeles, CA 90033

Join in person in BCC 101 or via Zoom at https://usc.zoom.us/meeting/register/tJAqdOmvrDwiHdZyplxWIV0xNNCRq_5LNYNp

Mammals are unable to regenerate the sensory hair cells of the inner ear, and loss of these cells due to aging, noise exposure and ototoxic drugs can cause irreversible deficits in hearing and balance.  We and others have shown that activation of hair cell transcription factors in supporting cells of the inner ear can reprogram these cells to a hair cell-like state. However, these new hair cells are not fully functional. I will describe a variety of approaches to try and overcome the barriers to faithful hair cell reprogramming in the ear, and how different approaches may be required for different kinds of damage to the ear.

Host: Andy McMahon

Event Type

Lecture / Talk / Workshop

Campus

Health Sciences Campus

Tags

stemcell

Department
Stem Cell at USC
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