USC Stem Cell Seminar: Zaven Kaprielian, Amgen—“Overview of Amgen Discovery Research and Neuroscience Therapeutic Area”

Tuesday, January 23, 2018 at 11:00am to 12:00pm

This is a past event.

Broad CIRM Center (BCC), First Floor Seminar Room
1425 San Pablo Street, Los Angeles, CA 90033

Amgen’s Discovery Research Unit takes a modality-independent, biology-first approach to prosecute a wide array of drug targets. In late 2012, Amgen acquired deCODE Genetics in Reykjavik, Iceland, and we exploit their unique capabilities to identify novel drug targets supported by strong human genetic validation. The Neuroscience Therapeutic Area is comprised of two closely integrated research groups located at the Amgen headquarters in Thousand Oaks, CA and at Amgen’s site in Cambridge, MA. Amgen Neuroscience is committed to serving patients by carrying out innovative science and unlocking the potential of biology, and is focused on developing new and effective therapeutics for neurodegenerative disorders (Alzheimer’s disease, Parkinson’s disease and ALS), migraine and chronic pain. Along with a strong early stage discovery pipeline across these areas, our late-stage Alzheimer’s disease group is preparing to carry out clinical studies in collaboration with Novartis to assess the ability of small molecule BACE (b-secretase) inhibitors to ameliorate disease symptoms, our migraine franchise is poised for approval of an anti-CGRPR mAb for the prevention of migraine headaches, and our late-stage discovery analgesia group has developed small molecule Nav1.7 inhibitors for the treatment of chronic pain.

Host: Justin Ichida

Live webcast at

Event Type

Lecture / Talk / Workshop


Health Sciences Campus



Stem Cell at USC
Add this to your calendar

Recent Activity