USC Stem Cell Seminar: James Monaghan PhD. Northeastern University-"Retinoic Acid Breakdown is Required to Maintain Positional Identity of the Regenerating Axolotl Limb"
Tuesday, March 28, 2023 11am to 12pm
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1425 San Pablo Street, Los Angeles, CA 90033#Stemcell
In-person or Register via Zoom at https://usc.zoom.us/meeting/register/tJAqdOmvrDwiHdZyplxWIV0xNNCRq_5LNYNp
Endogenous retinoic acid (RA) has been proposed to play a role in establishing positional axes during salamander limb regeneration. This presentation will provide evidence supporting the requirement for active degradation of RA to preserve the distal identity of regenerating cells. Furthermore, downstream targets of RA, which may regulate positional information, are identified and functionally tested.
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