Tuesday, February 13, 2018 at 11:00am to 12:00pm
Broad CIRM Center (BCC), First Floor Seminar Room
1425 San Pablo Street, Los Angeles, CA 90033
Altered tumor cell metabolism is now firmly established as a hallmark of human cancer. Downstream of oncogenic events, metabolism is re-wired to support cellular energetics and supply the building blocks for biomass. However, oncogenic activation and metabolic reprogramming also elicit cell intrinsic stresses, independent of the tumor microenvironment. I will summarize adaptive mechanisms co-opted by common oncogenes and tumor suppressors, to promote malignant progression.
Host: Wange Lu
Live webcast at keckmedia.usc.edu/stem-cell-seminar