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DESCRIPTION:In-person or Register via Zoom at https://usc.zoom.us/meeting/r
 egister/tJAqdOmvrDwiHdZyplxWIV0xNNCRq_5LNYNp\n\nTechnological limitations p
 recluded transcriptome-wide analyses of translation at single cell resoluti
 on. To solve this challenge\, we developed a novel microfluidic isotachopho
 resis approach\, named RIBOsome profiling via IsoTachoPhoresis (Ribo-ITP)\,
  and characterized translation in single oocytes and embryos during early m
 ouse development. Our high coverage measurements enabled the first analysis
  of allele-specific ribosome engagement in early development and led to the
  discovery of stage-specific differential engagement of zygotic RNAs with r
 ibosomes. The novel Ribo-ITP approach will enable numerous applications by 
 providing high coverage and high resolution ribosome occupancy measurements
  from ultra-low input samples including single cells.
DTEND:20221101T190000Z
DTSTAMP:20260305T201436Z
DTSTART:20221101T180000Z
GEO:34.061931;-118.203681
LOCATION:Broad CIRM Center (BCC)\, BCC- 101
SEQUENCE:0
SUMMARY:USC Stem Cell Seminar: Can Cenik\, PhD\, University of Texas at Aus
 tin- "Single cell quantification of ribosome occupancy and translation in d
 evelopment"
UID:tag:localist.com\,2008:EventInstance_40988964124749
URL:https://calendar.usc.edu/event/usc_stem_cell_seminar_can_cenik_phd_u_te
 xas_at_austin
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