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"Investigating and Modeling Respiratory Diseases Using Lung Stem Cells"

Unlike several other tissues and organs in the body, the adult lung is a quiescent organ whose ability to effectively regenerate after injury is unclear, despite evidence of repair in small animal models of lung injury. I will share examples of modeling respiratory diseases using human induced pluripotent stem cell (iPSC)-derived lung progenitors, and our efforts to elucidate the signaling pathways involved in adult lung injury and repair.