Tuesday, March 6, 2018 at 12:00pm to 1:00pm
In this USC Michelson Center for Convergent Bioscience seminar, Ali Khademhosseini of Bioengineering, Radiology, and Chemical and Biomolecular Engineering at UCLA will discuss his lab's efforts to engineer tissue regenerative therapies using hydrogels that can regulate cell behavior.
Khademhosseini and his team have developed hybrid hydrogels that can be photo-crosslinked and that combine natural biomolecules with nanoparticles to regulate the chemical, biological, mechanical and electrical properties of gels. These functional scaffolds induce the differentiation of stem cells to desired cell types and direct the formation of vascularized heart or bone tissues. They also have employed strategies to generate miniaturized tissues and developed directed assembly techniques to compile small tissue modules into larger constructs — work that may lead to next-generation regenerative therapeutics and biomedical devices.