1200 selected C. elegans genes, based on their orthology to human genes and potential neuronal function or known biochemical role (Chen et al., Neuron 2011; Kim et al., 2018). We identified numerous axon regeneration pathways. Among them, we have elucidated signaling pathways for DLK-1 MAP kinases, and characterized rapid cellular dynamics in response to axon injury. In this talk, I will describe new findings from the continued genetic screening, including several RNA binding factors."/> 1200 selected C. elegans genes, based on their orthology to human genes and potential neuronal function or known biochemical role (Chen et al., Neuron 2011; Kim et al., 2018). We identified numerous axon regeneration pathways. Among them, we have elucidated signaling pathways for DLK-1 MAP kinases, and characterized rapid cellular dynamics in response to axon injury. In this talk, I will describe new findings from the continued genetic screening, including several RNA binding factors.">

Molecular and Computational Biology Seminar: Yishi Jin, PhD (UC San Diego)

Friday, January 11 at 12:00pm to 1:00pm

This is a past event.

Irani Hall (RRI), 101
1050 Childs Way, Los Angeles, CA 90089

"Novel axon regeneration pathways in C. elegans"

Abstract: Using single axon injury assay in C. elegans, we systematically screened the function of >1200 selected C. elegans genes, based on their orthology to human genes and potential neuronal function or known biochemical role (Chen et al., Neuron 2011; Kim et al., 2018).  We identified numerous axon regeneration pathways. Among them, we have elucidated signaling pathways for DLK-1 MAP kinases, and characterized rapid cellular dynamics in response to axon injury.  In this talk, I will describe new findings from the continued genetic screening, including several RNA binding factors.

Event Type

Lecture / Talk / Workshop

Audience

Students, Alumni, Faculty/Staff

Campus

University Park Campus

Cost

Free

Department
Molecular and Computational Biology (MCB)
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