Friday, March 23, 2018 11am to 12pm
About this Event
3641 Watt Way, Los Angeles, CA 90089
Abstract:
G protein coupled receptors (GPCR) have proven a treasure trove for modern pharmacological intervention of numerous human ailments. However, in stark constrast to classically targeted GPCRs, adhesion GPCRs habe been largely neglected by biologists, pharmacologists and clinician scientists for decades. Only recently their physiological and signaling properties are being unravelled and show exciting features including their roles in tissue architecture, signaling through tethered agonism and their unusual activation through mechanical cues. This seminar will discuss the recent developments on adhesion GPCR signaling and introduce the receptor family as a topical area in neuroscience and cancer research.
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